Anti-ITGB2 monoclonal antibody, clone QOL-2

Antibody Isotype

IgG1

Clone

QOL-2

Species Reactivity

Pig

Immunogen

large granular lymphocytes (Pig)

Conjugate

Application Notes

Flow Cyt Use 10μl for 10⁶ cells.

Alternative Names

ITGB2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); integrin beta-2; CD18 leukocyte adhesion molecule; complement receptor C3 subunit beta; cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; CD18;

Entrez Gene ID

UniProt ID

Antigen Description

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.

Pathway

Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Legionellosis, organism-specific biosystem;