Anti-ITGB2 monoclonal antibody, clone UB-5

Antibody Isotype

IgG2a

Clone

UB-5

Species Reactivity

Rat

Immunogen

Rat CD18

Conjugate

Alternative Names

ITGB2; integrin, beta 2; integrin beta 2; CD18 leukocyte adhesion molecule; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; Cd18; MGC116306;

Entrez Gene ID

UniProt ID

Antigen Description

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.

Pathway

Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; IL-5 Signaling Pathway, organism-specific biosystem;