Anti-Proinsulin monoclonal antibody (DCABY-4175)

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
364730
Species Reactivity
Human
Immunogen
E. coli-derived recombinant human Proinsulin. Phe25-Asn110 Accession Number P01308
Conjugate
Unconjugated

Applications


Application Notes
ELISA Capture 2-8 μg/m; ELISA Detection 0.5-2.0 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-4175 - DCABY-4335
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
INS; insulin; ILPR; IRDN; IDDM1; IDDM2
Entrez Gene ID
UniProt ID

Product Background


Pathway
AGE/RAGE pathway; AMPK signaling pathway; ATF-2 transcription factor network; Adipogenesis; Aldosterone-regulated sodium reabsorption; Amyloids; Arf6 trafficking events; Cardiac Progenitor Differentiation;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Wan, Y; Datta, S; et al. Variable selection models based on multiple imputation with an application for predicting median effective dose and maximum effect. JOURNAL OF STATISTICAL COMPUTATION AND SIMULATION 85:1902-1916(2015).
Merono, T; Brites, F; et al. Metabolic alterations, HFE gene mutations and atherogenic lipoprotein modifications in patients with primary iron overload. CLINICAL SCIENCE 128:609-618(2015).

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