Specifications
Immunogen
Recombinant full length Human Hsc70 (amino acids 1-646) produced in HEK293T cells.
Applications
Application Notes
WB: 1/1000; IHC-P: 1/150;
Target
Alternative Names
HSPA8; heat shock 70kDa protein 8; heat shock 70kD protein 8 , HSPA10; heat shock cognate 71 kDa protein; HSC70; HSC71; HSP73; LPS-associated protein 1; heat shock 70kd protein 10; heat shock cognate protein 54; constitutive heat shock protein 70; lipopol
Product Background
Antigen Description
Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Isoform 2 may function as an endogenous inhibitory regulator of HSC70 by competing the co-chaperones.
Pathway
Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem; Clathrin derived vesicle budding, organism-specific biosystem; Destabilization of mRNA by AUF1 (hnRNP D0), organism-specific biosystem; Diurnally regulated genes with circadian orthologs, organism-specific biosystem; Endocytosis, organism-specific biosystem;
Citations
Publication ()
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COA
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