Anti-HSPA8 monoclonal antibody, clone 2H3

Antibody Isotype

IgG2a

Clone

2H3

Species Reactivity

Human

Immunogen

HSPA8 (AAH16660, 1 a.a. ~ 646 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

HSPA8; heat shock 70kDa protein 8; heat shock 70kD protein 8 , HSPA10; heat shock cognate 71 kDa protein; HSC70; HSC71; HSP73; LPS-associated protein 1; heat shock 70kd protein 10; heat shock cognate protein 54; constitutive heat shock protein 70; lipopol

Entrez Gene ID

UniProt ID

Antigen Description

The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date.

Pathway

Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem; Clathrin derived vesicle budding, organism-specific biosystem; Destabilization of mRNA by AUF1 (hnRNP D0), organism-specific biosystem; Diurnally regulated genes with circadian orthologs, organism-specific biosystem; Endocytosis, organism-specific biosystem;