Specifications
Species Reactivity
Mouse; Rat; Sheep; Rabbit; Chicken; Guinea pig; Cow; Dog; Human; P. polycephalum
Immunogen
Full length native Hsc70 protein (Hamster) purified from sodium arsenite treated heat-resistant variants of Chinese hamster cells.
Applications
Application Notes
IHC-Fr: 5 μg/ml; Flow Cyt: 1μg/106 cells; WB: 0.1 μg/ml; IP: 5 μg/ml; ICC: 5 μg/ml.
Target
Alternative Names
HSPA8; heat shock protein 8; heat shock cognate 71 kDa protein; heat shock cognate hsc73; heat shock 70kD protein 8; heat shock 70 kDa protein 8; heat shock protein cognate 70; Hsc70; Hsc71; Hsc73; Hsp73; Hspa10; 2410008N15Rik; MGC102007; MGC106514; MGC11
Product Background
Antigen Description
Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Isoform 2 may function as an endogenous inhibitory regulator of HSC70 by competing the co-chaperones.
Pathway
Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Circadian Exercise, organism-specific biosystem; Clathrin derived vesicle budding, organism-specific biosystem; Diurnally regulated genes with circadian orthologs, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem;
Citations
Publication ()
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COA
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