Anti-G6PD polyclonal antibody, clone O3D2

Antibody Isotype

IgG

Clone

O3D2

Species Reactivity

Human

Immunogen

Recombinant fragment corresponding to a region within amino acids 100 and 322 of G6PD (Uniprot ID#P11413)

Conjugate

Application Notes

ELISA, Pr*, IHC-P, WB
We recommend the following for sandwich ELISA (Capture - Detection):
DPABY-718 - DPABY-744

Alternative Names

G6PD; glucose-6-phosphate dehydrogenase; G6PD1; glucose-6-phosphate 1-dehydrogenase;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Pathway

Carbon metabolism; Disease; Glutathione metabolism; Glycogen storage diseases; Metabolism; Metabolism of carbohydrates; Myoclonic epilepsy of Lafora; Pentose Phosphate Pathway;