Specifications
Immunogen
Recombinant protein corresponding to human EPO.
Applications
Application Notes
ELISA (1:10000); WB (1:500-1:2000); Immunofluorescence (1:200-1:1000); The optimal working dilution should be determined by the end user.
Target
Alternative Names
EPO; erythropoietin; EP; epoetin; MVCD2; MGC138142;
Product Background
Antigen Description
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.
Pathway
Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; EPO Receptor Signaling, organism-specific biosystem; EPO signaling pathway, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem; Hematopoietic cell lineage, organism-specific biosystem;
Citations
Publication ()
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COA
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