Anti-eIF4EBP1 monoclonal antibody (CAB-7614MH)

Mouse anti-Human eIF4EBP1 monoclonal antibody for ELISA, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
MAAG5421
Species Reactivity
Human
Immunogen
Purified recombinant fragment of 4EBP1 expressed in E. Coli.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1:10000-50000
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; 4E BP1; PHAS I; phosphorylated heat and acid stable protein regulated by insulin 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
AMPK signaling, organism-specific biosystem; Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem;

Citations


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References


Castellvi, J; Garcia, A; et al. Phosphorylated 4E binding protein 1: A hallmark of cell signaling that correlates with survival in ovarian cancer. CANCER 107:1801-1811(2006).
Rider, MH; Hussain, N; et al. Phosphorylation of translation factors in response to anoxia in turtles, Trachemys scripta elegans: role of the AMP-activated protein kinase and target of rapamycin signalling pathways. MOLECULAR AND CELLULAR BIOCHEMISTRY 332:207-213(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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