EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; 4E BP1; PHAS I; phosphorylated heat and acid stable protein regulated by insulin 1; eIF4E-binding protein 1; phosphoryl
Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Pathway
AMPK signaling; Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S; Acute myeloid leukemia; Alpha6-Beta4 Integrin Signaling Pathway; Cap-dependent Translation Initiation; ErbB signaling pathway;
Citations
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