Anti-eIF4EBP1 monoclonal antibody (CAB-7613MH)
Mouse anti-Human eIF4EBP1 monoclonal antibody for ELISA, WB, IHC
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Human, Mouse, Rat
Purified recombinant fragment of 4E-BP1 expressed in E. Coli.
WB: 1:500-2000; IHC: 1:50-100
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; 4E BP1; PHAS I; phosphorylated heat and acid stable protein regulated by insulin 1
AMPK signaling, organism-specific biosystem; Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem;
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Welle, S; Burgess, K; et al. Stimulation of skeletal muscle myofibrillar protein synthesis, p70 S6 kinase phosphorylation, and ribosomal protein S6 phosphorylation by inhibition of myostatin in mature mice. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 296:E567-E572(2009).
Duncan, RF; Song, HJP; et al. Striking multiplicity of eIF4E-BP1 phosphorylated isoforms identified by 2D gel electrophoresis - Regulation by heat shock. EUROPEAN JOURNAL OF BIOCHEMISTRY 265:728-743(1999).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.