Like CD80, CD86 is an accessory molecule which functions in the CD28-CD80/CD86 co-stimulatory pathway, vital for T cell activation, crosstalk between T and B cells, and Th2-mediated Ig production.
Pathway
Adaptive Immune System; Allograft rejection; Autoimmune thyroid disease; CD28 co-stimulation; CD28 dependent PI3K/Akt signaling; CD28 dependent Vav1 pathway; CTLA4 inhibitory signaling; Cell adhesion molecules (CAMs); Constitutive PI3K/AKT Signaling in Cancer; Costimulation by the CD28 family; DAP12 interactions; DAP12 signaling; Disease; Downstream Signaling Events Of B Cell Receptor (BCR); Downstream signal transduction; Downstream signaling of activated FGFR; Fc epsilon receptor (FCERI) signa
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