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The minimum detectable dose of Rat CD86 / B7-2 was determined to be approximately 4.7 pg/ml. This is defined as at least three times standard deviations above the mean optical density of 10 replicates of the zero standard.
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Lagana, B; Vinciguerra, M; et al. Modulation of T-Cell Co-Stimulation in Rheumatoid Arthritis Clinical Experience with Abatacept. CLINICAL DRUG INVESTIGATION 29:185-202(2009).
Dai, H; Zhu, HF; et al. Programmed Death-1 Signaling Is Essential for the Skin Allograft Protection by Alternatively Activated Dendritic Cell Infusion in Mice. TRANSPLANTATION 88:864-873(2009).