Specifications
Species Reactivity
Mouse; Rat; Dog; Human
Immunogen
Recombinant full length Human CD2 (amino acids 1-351) produced in HEK293T cells (NP_001758).
Applications
Application Notes
WB: 1/2000 - 1/4000; IHC-P: 1/500;
Target
Alternative Names
CD2; CD2 molecule; CD2 antigen (p50), sheep red blood cell receptor , SRBC; T-cell surface antigen CD2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red b
Product Background
Antigen Description
CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
Pathway
Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Hemostasis, organism-specific biosystem; T Cell Receptor Signaling Pathway, organism-specific biosystem;
Citations
Publication ()
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COA
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