Anti-CASP3 monoclonal antibody (DCABH-8571) Knockout Validated

Rabbit anti-Human CASP3 monoclonal antibody for ICC/IF, WB, IHC-P, IP, FC, ICC

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
F94-214
Species Reactivity
Mouse, Human
Immunogen
A synthetic peptide corresponding to residues following Ser29 of human caspase-3 (N-terminus of p17 subunit).
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 5 μg/ml; WB: 1/10000; IP: 1/100; Flow Cyt: 1/50; ICC: 1/250.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CASP3; caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis related cysteine protease; caspase-3; apopain; CPP32
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of DNA fragmentation factor, organism-specific biosystem; Activation of caspases through apoptosome-mediated cleavage, organism-specific biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Lirussi, F; Rakotoniaina, Z; et al. ADRB3 adrenergic receptor is a key regulator of human myometrial apoptosis and inflammation during chorioamnionitis. BIOLOGY OF REPRODUCTION 78:497-505(2008).
Kolobov, VV; Davydova, TV; et al. Protective action of glutamate antibodies on increased expression of genes of programmed death of rat brain cells induced by injection of a beta-amyloid fragment (25-35). BIOLOGY BULLETIN 41:118-125(2014).

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