Anti-CASP3 monoclonal antibody (DMAB5437MH)

Mouse anti-Human CASP3 monoclonal antibody for IHC, IP, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
4DTQ04
Species Reactivity
Human
Immunogen
BALB/C mice were injected with recombinant full length human Caspase 3 protein.
Conjugate
Unconjugated

Target


Alternative Names
CASP3; caspase 3, apoptosis-related cysteine peptidase; CPP32; SCA-1; CPP32B; SREBP cleavage activity 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of DNA fragmentation factor; Activation of caspases through apoptosome-mediated cleavage; Alpha6-Beta4 Integrin Signaling Pathway; Alzheimer"s disease; Amoebiasis; Androgen Receptor Signaling Pathway; Amyotrophic lateral sclerosis (ALS); Apopto

Citations


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References


Machaalani, R; Radford, JL; et al. Tissue fixation effects on lmmunohistochemical staining of caspase-3 in brain tissue. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY 15:463-470(2007).
Li, A; Felix, JC; et al. Menstrual-like breakdown and apoptosis in human endometrial explants. HUMAN REPRODUCTION 20:1709-1719(2005).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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