Anti-CASP3 polyclonal antibody (DPABH-01435) Knockout Validated

Rabbit Anti-Human CASP3 (aa 150-250) polyclonal antibody for ICC/IF, IHC-P, IHC-Fr, FC, ICC, IHC (PFA fixed), IHC-FoFr, WB, IHC-Wmt Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Mouse, Rat, Human, Pig, Xenopus laevis, Fruit fly, Indian Muntjac, Zebrafish, Rhesus monkey, Marmoset, Schmidtea mediterranea, Salvelinus alpinus
Immunogen
Synthetic peptide conjugated to KLH derived from within residues 150 - 250 of Human active Caspase 3.
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 5 μg/ml; IHC-P: 1/50; WB: 1/1000 - 1/2000; IHC (PFA fixed): 1/300; IHC-FoFr: 1/300; IHC - Wholemount: 1/500
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CASP3; caspase 3, apoptosis-related cysteine peptidase; CPP32; SCA-1; CPP32B; caspase-3
Entrez Gene ID
UniProt ID

Product Background


Pathway
AGE/RAGE pathway; Activation of caspases through apoptosome-mediated cleavage; Alzheimers disease; Alzheimers Disease

Citations


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References


Love, S; Barber, R; et al. Neuronal death in brain infarcts in man. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 26:55-66(2000).
Yi, B; Zhang, M; et al. Mechanisms of the apoptosis induced by CD176 antibody in human leukemic cells. INTERNATIONAL JOURNAL OF ONCOLOGY 38:1565-1573(2011).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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