Recombinant SARS-CoV-2 3C-like Proteinase [His] (DAGC166)

Recombinant SARS-CoV-2 3C-like Proteinase from E.coli [His]

Product Overview
Recombinant SARS-CoV-2 3C-like Proteinase is produced by our E.coli expression system and the target gene encoding Ser1-Gln306 is expressed with a 6His tag at the N-terminus.
Target
SARS-CoV-2 3C-like Proteinase
Nature
Recombinant
Tag/Conjugate
His
Endotoxin
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Alternative Names
M Proteinase; 3CL Proteinase; SARS-CoV 2; SARS-CoV 2 3CL pro
Procedure
1mM EDTA
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Format
Liquid
Buffer
Supplied as a 0.2 um filtered solution of PBS, 1mM EDTA, 10% Glycerol, pH 7.4.
Preservative
None
Storage
Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Introduction
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.
Keywords
M Proteinase; 3CL Proteinase; SARS-CoV 2; SARS-CoV 2 3CL pro

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