Product Overview
E. coli-derived SARS-CoV-2 3CL Protease protein, Ser3264 - Gln3569
Target
SARS-CoV-2 3C-like Proteinase
Tag/Conjugate
unconjugated
Alternative Names
M Proteinase; 3CL Proteinase; SARS-CoV-2; SARS-CoV-2 3CL pro; SARS-CoV-2 3CL
Purity
>95%, by SDS-PAGE under reducing conditions
Buffer
1.7 mg/ml (50 uM) in 50 mM HEPES, pH 7.5, 150 mM NaCl, 1 mM DTT, 1 mM EDTA
Storage
100 months from date of receipt, -70°C as supplied.
3 months, -70°C under sterile conditions after opening.
Introduction
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.
Keywords
M Proteinase; 3CL Proteinase; SARS-CoV-2; SARS-CoV-2 3CL pro; SARS-CoV-2 3CL
Citations
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