Specifications
Species Reactivity
Human, Mouse
Immunogen
full length recombinant human HMGB1
Applications
Application Notes
FC, IHC-P, WB
Each laboratory should determine an optimum working titer for use in its particular application.
Other applications have not been tested but use in such assays should not necessarily be excluded.
Target
Alternative Names
HMGB1; high mobility group box 1; high mobility group (nonhistone chromosomal) protein2, high mobility group box2, HMG1; high mobility group protein B1; Amphoterin; DKFZp686A04236; high mobility group protein 1; HMG3; SBP 1; Sulfoglucuronyl carbohydrate
Product Background
Pathway
Activated TLR4 signalling, organism-specific biosystem; Activation of DNA fragmentation factor, organism-specific biosystem; Advanced glycosylation endproduct receptor signaling, organismspecific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis induced DNA fragmentation, organismspecific biosystem; Apoptotic executionphase, organism-specific biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Yamada, S; Yakabe, K; et al. New high mobility group box 1 assay system. CLINICA CHIMICA ACTA 372:173-178(2006).
Ueno, H; Matsuda, T; et al. Contributions of high mobility group box protein in experimental and clinical acute lung injury. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 170:1310-1316(2004).
COA
Certificate of Analysis
