Anti-HMGB1 monoclonal antibody (DMABT-H13957)
Mouse anti-Human HMGB1 monoclonal antibody for WB, IHC, IF, sELISA, ELISA
Datasheet
Specifications
Host Species
Mouse
Antibody Isotype
IgG2a
Clone
2E6
Species Reactivity
Human
Immunogen
HMGB1 (AAH03378.1,2a.a. ~ 215 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Target
Alternative Names
HMGB1; high mobility group box 1; high mobility group (nonhistone chromosomal) protein2, high mobility group box2, HMG1; high mobility group protein B1; Amphoterin; DKFZp686A04236
Entrez Gene ID
UniProt ID
Product Background
Pathway
Activated TLR4 signalling, organism-specific biosystem; Activation of DNA fragmentation factor, organism-specific biosystem; Advanced glycosylation endproduct receptor signaling, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis induced DNA fragmentation, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem;
Citations
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References
Ito, I; Mitsuoka, N; et al. Conformational difference in HMGB1 proteins of human neutrophils and lymphocytes revealed by epitope mapping of a monoclonal antibody. JOURNAL OF BIOCHEMISTRY 136:155-162(2004).
Yamada, S; Yakabe, K; et al. New high mobility group box 1 assay system. CLINICA CHIMICA ACTA 372:173-178(2006).
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Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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