NFATC4 blocking peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

NFATC4 peptide is a synthetic peptide cooresponding to 15 amino acids from an internal region of NFATC4.

Purity

> 95 % by SDS-PAGE.

Format

Lyophilized

Preservative

None

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Reconstitution

NFATC4 peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.

Introduction

This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Entrez Gene ID

Synonyms

NFATC4; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; NFAT3; NF-AT3; NF-ATC4; nuclear factor of activated T-cells, cytoplasmic 4; T-cell transcription factor NFAT3;