Anti-NFATC4 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human NFATC4 is used for rabbit immunization.

Conjugate

Alternative Names

NFATC4; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; nuclear factor of activated T-cells, cytoplasmic 4; NFAT3; NF-AT3; T cell transcription factor NFAT3; T-cell transcription factor NFAT3; NF-ATc4;

Entrez Gene ID

UniProt ID

Antigen Description

The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Pathway

Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; ErbB2/ErbB3 signaling events, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem;