Human MyD88 blocking peptide

Product Overview

Myd88 ( internal ) peptide ( human )

Target

MyD88

Nature

Synthetic

Tag/Conjugate

Unconjugated

Concentration

0.2 mg/ml

Buffer

PBS with 0.1% BSA 0.02% sodium azide pH7.2

Preservative

0.02% Sodium Azide

Storage

Upon receipt - Keep as concentrated solution. Aliquot and store at -20℃ or below. Avoid freeze-thaw cycles.

Gene ID

4615

UniProt ID

Q99836

Antigen Description

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Function

TIR domain binding; Toll binding; death receptor binding; identical protein binding; protein binding;

Synonyms

MYD88; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88; MYD88D;