Specifications
Immunogen
Recombinant protein corresponding to amino acids 1-309 of human MYD88.
Applications
Application Notes
WB (1:1000) & The optimal working dilution should be determined by the end user.
Target
Alternative Names
MYD88; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88; MYD88D;
Product Background
Antigen Description
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway.
Pathway
Activated TLR4 signalling, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Chagas disease (American tr
Citations
Publication ()
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COA
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