Specifications
Immunogen
Recombinant protein corresponding to amino acids 933-1065 of human CP.
Applications
Application Notes
WB (1:1000); The optimal working dilution should be determined by the end user.
Target
Alternative Names
ceruloplasmin (ferroxidase); OTTHUMP00000215841; EC 1.16.3.1; ceruloplasmin; CP-2; Ferroxidase; OTTHUMP00000215840; OTTHUMP00000197026
Product Background
Antigen Description
The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities.
Mouse monoclonal antibody raised against partial recombinant CP.
Pathway
HIF-1-alpha transcription factor network, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Metal ion SLC transporters, organism-specific biosystem; Porphyrin and chlorophyll metabolism, organism-specific biosystem; Porphyrin and chlorophyll metabolism, conserved biosystem; SLC-mediated transmembrane transport, organism-specific biosystem
Citations
Publication ()
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COA
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