Product Overview
Recombinant Human Papilloma Virus Type 18 (HPV18), L1 Protein. Immunoreactivity is confirmed by reaction in quantitative immunoblot with monoclonal antibody specific to HPV L1. Does not contain a fusion partner.
Tag/Conjugate
Unconjugated
Alternative Names
HPV18 L1 Protein; HPV L1; HPV18; HPV; HPV18 L1
Purity
> 90% pure (SDS-PAGE). Purification from broken yeast cells by the following scheme: clarification, ammonium sulfate precipitation, ultrafiltration, cation exchange chromatography, zonal centrifugation, size exclusion chromatography and filtration.
Buffer
20 mM Potassium Dihydrogen Phosphate (KH2PO4), pH 7.2 containing 500 mM Sodium Chloride, 1.7 mM EDTA, 0.01% Tween-80 and 1 mM 2-Mercaptoethanol.
Storage
Store at -20°C. Aliquot to avoid multiple freeze/thaw cycles.
Introduction
L1 is a major capsid protein of type 18 human papilloma virus. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies.
Keywords
HPV18 L1 Protein; HPV L1; HPV18; HPV; HPV18 L1
Citations
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