Anti-GBA monoclonal antibody (DMABT-H13823)
Mouse anti-Human GBA monoclonal antibody for WB, IHC, IF, sELISA, ELISA
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GBA (NP_000148, 146 a.a. ~ 235 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
GBA; glucosidase, beta, acid; GLUC, glucosidase, beta; acid (includes glucosylceramidase) , glucosylceramidase; glucosylceramidase; GBA1
GBA (Glucosylceramidase Beta) is a Protein Coding gene. Diseases associated with GBA include gaucher disease, type i and gaucher disease, type ii. Among its related pathways are Metabolism and Transport to the Golgi and subsequent modification. GO annotations related to this gene include receptor binding and glucosylceramidase activity. This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Glycosphingolipid metabolism, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Other glycan degradation, organism-specific biosystem.
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Zaripov, MM; Morenkov, OS; et al. Glycoprotein B of Aujeszky's disease virus: Topographical epitope mapping and epitope-specific antibody response. RESEARCH IN VIROLOGY 149:29-41(1998).
BRADBURY, A; MILSTEIN, C; et al. CHROMOSOMAL LOCALIZATION OF CD1D GENES IN THE MOUSE. SOMATIC CELL AND MOLECULAR GENETICS 17:93-96(1991).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.