Native Bordetella Pertussis Toxin

Product Overview

Native Bordetella pertussis toxin, purified from Bordetella pertussis (strain NCTC 10739)

Target

B. pertussis Toxin

Nature

Native

Tag/Conjugate

Unconjugated

Alternative Names

Pertussis toxin; PT; Islet-activating protein; PTX

Purity

> 98%

Format

Lyophilized powder. Contains 0.05M sodium phosphate and 0.5M sodium chloride.

Storage

Store at 2-8°C

Introduction

Bordetella pertussis is a Gram-negative, aerobic coccobacillus capsulate of the genus Bordetella, and the causative agent of pertussis or whooping cough. Unlike B. bronchiseptica, B. pertussis is nonmotile. Its virulence factors include pertussis toxin, filamentous hemagglutinin, pertactin, fimbria, and tracheal cytotoxin. There does not appear to be a zoonotic reservoir for B. pertussis—humans are its only host. The bacterium is spread by airborne droplets; its incubation period is seven to 14 days.

Keywords

IAP S1; Islet-activating protein S1; NAD-dependent ADP-ribosyltransferase; B. pertussis PT protein; Bordetella pertussis toxin; pertussis; B. pertussis