Anti-TP53 monoclonal antibody (DCABH-4289) Knockout Validated

Mouse Anti-Human TP53 monoclonal antibody for WB, IP, FC, ICC, ELISA

Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
0E4EF4
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to amino acids 1-24 of Human p53
Conjugate
Unconjugated

Applications


Application Notes
WB: 2 μg/ml; ICC: 1 μg/ml; In-Cell ; IHC-P: 1 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
TP53; tumor protein p53; cellular tumor antigen p53; LFS1; Li Fraumeni syndrome; p53
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of BH3-only proteins, organism-specific biosystem; Activation of NOXA and translocation to mitochondria, organism-specific biosystem; Activation of PUMA and translocation to mitochondria, organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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Mouse IgG2a Isotype Control DAGIC1216 FC EIA IHC Mouse PDF Inquiry

References


He, LZ; Lai, HQ; et al. Dual-function nanosystem for synergetic cancer chemo-/radiotherapy through ROS-mediated signaling pathways. BIOMATERIALS 51:30-42(2015).
Strauss, BS; et al. Silent and multiple mutations in p53 and the question of the hypermutability of tumors. CARCINOGENESIS 18:1445-1452(1997).

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