Anti-TP53 monoclonal antibody (DMAB6436MH)

Mouse Anti-TP53 monoclonal antibody for IHC-Fr, IHC(PFA fixed), WB, IP, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
Cq54-12
Species Reactivity
N/A
Conjugate
Unconjugated

Target


Alternative Names
TP53; tumor protein p53; P53; LFS1; TRP53; cellular tumor antigen p53
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of BH3-only proteins; Activation of NOXA and translocation to mitochondria; Activation of PUMA and translocation to mitochondria; Amyotrophic lateral sclerosis (ALS); Androgen Receptor Signaling Pathway; Apoptosis; Aurora A signaling; Autodegra

Citations


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References


Gotte, K; Riedel, F; et al. The relationship between allelic imbalance on 17p, p53 mutation and p53 overexpression in head and neck cancer. INTERNATIONAL JOURNAL OF ONCOLOGY 19:331-336(2001).
Oliveras-Ferraros, C; Vazquez-Martin, A; et al. Growth and molecular interactions of the anti-EGFR antibody Cetuximab and the DNA cross-linking agent cisplatin in gefitinib-resistant MDA-MB-468 cells: New prospects in the treatment of triple-negative/basal-like breast cancer. INTERNATIONAL JOURNAL OF ONCOLOGY 33:1165-1176(2008).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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