Post-translational modification of proteins and peptides is a robust way to regulate function of existing proteins or peptides.Methylation on lysine residues is one example of post-translational modification and is performed by a variety of protein methyltransferases in the cell. C/EBPs are extensively modified by methylation of lysine side chains and this regulated methylation profoundly affects the activity of C/EBPs.
Pathway
Activation of BH3-only proteins, organism-specific biosystem; Activation of NOXA and translocation to mitochondria, organism-specific biosystem; Activation of PUMA and translocation to mitochondria, organism-specific biosystem; Amyotrophic lateral scleros
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