Anti-THRA polyclonal antibody (DPABH-20945)

Rabbit anti-Human THRA (aa 246-295) polyclonal antibody for WB, IHC-P Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to a region within internal sequence amino acids 246-295 of Human Thyroid Hormone Receptor alpha 1+2 (DQIILLKGCC MEIMSLRAAV RYDPESDTLT LSGEMAVKRE QLKNGGLGVV).
Conjugate
Unconjugated

Applications


Application Notes
WB: 0.5 μg/ml; IHC-P: 4 - 8 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
THRA; thyroid hormone receptor, alpha; AR7; EAR7; ERBA; CHNG6
Entrez Gene ID
UniProt ID

Product Background


Pathway
Endochondral Ossification; Generic Transcription Pathway; Neuroactive ligand-receptor interaction; Nuclear Receptors

Citations


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References


Sato, K; Yamazaki, K; et al. Immunoglobulins of untreated Graves' patients with or without thyrotropin receptor antibody (determined by porcine thyrocytes) universally elicit potent thyroid hormone-releasing activity in cultured human thyroid follicles. THYROID 9:979-988(1999).
Wallis, K; Dudazy, S; et al. The Thyroid Hormone Receptor alpha 1 Protein Is Expressed in Embryonic Postmitotic Neurons and Persists in Most Adult Neurons. MOLECULAR ENDOCRINOLOGY 24:1904-1916(2010).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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