Anti-THRA monoclonal antibody (CABT-B1489)

Mouse Anti-Human THRA monoclonal antibody for IHC-P, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
O504/74
Species Reactivity
Human, Rat, Mouse
Immunogen
Recombinant full-length human thyroid hormone receptor Alpha-1 isoform.
Conjugate
unconjugated

Applications


Application Notes
WB: 1.0 µg/mL from a representative lot detected thyroid hormone receptor in 10 µg of human and rat brain tissue lysates.
IHC: An 1:250 dilution from a representative lot detected thyroid hormone receptor in human cerebral cortex, mouse cerebellum, and rat kidney tissue.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
THRA; thyroid hormone receptor, alpha; AR7; ERBA; CHNG6
Entrez Gene ID
UniProt ID

Citations


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References


Sato, K; Yamazaki, K; et al. Immunoglobulins of untreated Graves' patients with or without thyrotropin receptor antibody (determined by porcine thyrocytes) universally elicit potent thyroid hormone-releasing activity in cultured human thyroid follicles. THYROID 9:979-988(1999).
Wallis, K; Dudazy, S; et al. The Thyroid Hormone Receptor alpha 1 Protein Is Expressed in Embryonic Postmitotic Neurons and Persists in Most Adult Neurons. MOLECULAR ENDOCRINOLOGY 24:1904-1916(2010).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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