Anti-SQSTM1 polyclonal antibody (DPAB-L21188)

Rabbit anti-Human SQSTM1 (C-terminal) polyclonal antibody for IHC

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
SQSTM1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human SQSTM1.
Conjugate
Unconjugated

Target


Alternative Names
SQSTM1; sequestosome 1; p60; p62; A170; OSIL
Entrez Gene ID
UniProt ID

Product Background


Pathway
BDNF signaling pathway; Cell death signalling via NRAGE; Cytokine Signaling in Immune system; IL1-mediated signaling events; Immune System; Interleukin-1 signaling; NF-kB is activated and signals survival; NRIF signals cell death from the nucleus

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References


Tanji, K; Maruyama, A; et al. Keap1 Is Localized in Neuronal and Glial Cytoplasmic Inclusions in Various Neurodegenerative Diseases. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 72:18-28(2013).
Tanji, K; Zhang, HX; et al. p62/sequestosome 1 binds to TDP-43 in brains with frontotemporal lobar degeneration with TDP-43 inclusions. JOURNAL OF NEUROSCIENCE RESEARCH 90:2034-2042(2012).

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