Anti-SQSTM1 polyclonal antibody (DPAB-L21188)

Rabbit anti-Human SQSTM1 (C-terminal) polyclonal antibody for IHC Datasheet

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Specifications


Host Species
Rabbit
Species Reactivity
Human
Immunogen
SQSTM1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human SQSTM1.
Conjugate
Unconjugated

Target


Alternative Names
SQSTM1; sequestosome 1; p60; p62; A170; OSIL
Entrez Gene ID
UniProt ID

Product Background


Pathway
BDNF signaling pathway; Cell death signalling via NRAGE; Cytokine Signaling in Immune system; IL1-mediated signaling events; Immune System; Interleukin-1 signaling; NF-kB is activated and signals survival; NRIF signals cell death from the nucleus

Citations


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References


Narendra, DP; Kane, LA; et al. p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both. AUTOPHAGY 6:1090-1106(2010).
Tanji, K; Zhang, HX; et al. p62/sequestosome 1 binds to TDP-43 in brains with frontotemporal lobar degeneration with TDP-43 inclusions. JOURNAL OF NEUROSCIENCE RESEARCH 90:2034-2042(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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