Anti-SQSTM1 monoclonal antibody (DCABH-1079)

Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
6E6
Species Reactivity
Human
Immunogen
Full length recombinant protein of Human SQSTM1/ p62 produced in HEK293T cell.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/2000; IHC-P: 1/150;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SQSTM1; sequestosome 1; OSIL, oxidative stress induced like , Paget disease of bone 3 , PDB3; sequestosome-1; A170; p60
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; IL1-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Interleukin-1 signaling, organism-specific biosystem; NF-kB is activated and signals survival, organism-specific biosystem; NRIF signals cell death from the nucleus, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Martinet, W; Schrijvers, DM; et al. Immunohistochemical analysis of macroautophagy Recommendations and limitations. AUTOPHAGY 9:386-402(2013).
Shen, CC; Wang, WZ; et al. Chloroquine blocks the autophagic process in cisplatin-resistant osteosarcoma cells by regulating the expression of p62/SQSTM1. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 32:448-456(2013).

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