Anti-SQSTM1 polyclonal antibody (DPABH-05303)
Rabbit anti-Human SQSTM1 (aa 157-251) polyclonal antibody for WB, ICC/IF
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Mouse, Rat, Human, Zebrafish
Synthetic peptide, corresponding to a region within internal amino acids 157-251 of Human SQSTM1/ p62 (UniProt: Q13501).
WB: 1/500 - 1/3000; ICC/IF: 1/100 - 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
SQSTM1; sequestosome 1; p60; p62; A170; OSIL
BDNF signaling pathway; Cytokine Signaling in Immune system; Immune System; NF-kB is activated and signals survival
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Tanji, K; Zhang, HX; et al. p62/sequestosome 1 binds to TDP-43 in brains with frontotemporal lobar degeneration with TDP-43 inclusions. JOURNAL OF NEUROSCIENCE RESEARCH 90:2034-2042(2012).
Shen, CC; Wang, WZ; et al. Chloroquine blocks the autophagic process in cisplatin-resistant osteosarcoma cells by regulating the expression of p62/SQSTM1. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 32:448-456(2013).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.