Anti-SQSTM1 polyclonal antibody (DPABH-05303)

Rabbit anti-Human SQSTM1 (aa 157-251) polyclonal antibody for WB, ICC/IF Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Mouse, Rat, Human, Zebrafish
Immunogen
Synthetic peptide, corresponding to a region within internal amino acids 157-251 of Human SQSTM1/ p62 (UniProt: Q13501).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/3000; ICC/IF: 1/100 - 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SQSTM1; sequestosome 1; p60; p62; A170; OSIL
Entrez Gene ID
UniProt ID

Product Background


Pathway
BDNF signaling pathway; Cytokine Signaling in Immune system; Immune System; NF-kB is activated and signals survival

Citations


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References


Tanji, K; Zhang, HX; et al. p62/sequestosome 1 binds to TDP-43 in brains with frontotemporal lobar degeneration with TDP-43 inclusions. JOURNAL OF NEUROSCIENCE RESEARCH 90:2034-2042(2012).
Shen, CC; Wang, WZ; et al. Chloroquine blocks the autophagic process in cisplatin-resistant osteosarcoma cells by regulating the expression of p62/SQSTM1. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 32:448-456(2013).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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