Secreted protein acidic and rich incysteine/osteonectin/BM40, or SPARC, is a matrix-associated proteinthat elicits changes in cell shape, inhibits cell-cycleprogression, and influences the synthesis of extracellular matrix(ECM).
Pathway
Binding and Uptake of Ligands by Scavenger Receptors; ECM proteoglycans; Extracellular matrix organization; Hemostasis; Platelet activation, signaling and aggregation; Platelet degranulation; Response to elevated platelet cytosolic Ca2+; Scavenging by Class H Receptors;
Citations
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