Specifications
Immunogen
SERPING1 (AAH11171, 1 a.a. ~ 501 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Applications
Application Notes
WB: 1:500-1000
Target
Alternative Names
SERPING1; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; C1NH, serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary); plasma protease C1 inhibitor; angioedema; hereditary; C1 INH; C1IN; HAE1;
Product Background
Antigen Description
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
Pathway
Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; Hemostasis, organism-specific biosystem; Intrinsic Pathway, organism-specific biosystem; Pertussis, organism-specific biosystem;
Citations
Publication ()
Have you cited CAB-4608MH in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
