Specifications
Immunogen
The details of the immunogen for this antibody are not available.
Applications
Application Notes
WB: 1/10 - 1/50; IHC-Fr: 1/10 - 1/50; Flow Cyt: 1/10 - 1/50;
Target
Alternative Names
SERPING1; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; C1NH,serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary); plasma protease C1 inhibitor; angioedema; hereditary; C1 INH; C1IN; HAE1; H
Product Background
Antigen Description
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
Pathway
Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; Hemostasis, organism-specific biosystem; Intrinsic Pathway, organism-specific biosystem; Pertussis, organism-specific biosystem; Pertussis, conserved biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem
Citations
Publication ()
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COA
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