Synthetic peptide: SLEDLKVDKVIQAQ-C, corresponding to N terminal amino acids 6-19 of Human Syntenin isoforms 1 (NP_005616.2 and NP_001007068.1) and 3 (NP_001007070.1 and NP_001007071.1).
Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.
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