Anti-SDCBP (aa 1-100) polyclonal antibody

Species Reactivity

Human

Immunogen

SDCBP (NP_005616, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. The sequence is MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGND

Conjugate

Alternative Names

SDCBP; syndecan binding protein (syntenin); ST1; SYCL; MDA-9; TACIP18; syntenin-1; scaffold protein Pbp1; syndecan-binding protein 1; melanoma differentiation associated protein-9; melanoma differentiation-associated protein 9; pro-TGF-alpha cytoplasmic d

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.

Pathway

Axon guidance; IL-5 Signaling Pathway; Neurofascin interactions; Syndecan-2-mediated signaling events