Specifications
Immunogen
Recombinant full length protein of Human Syntenin produced in HEK293T cells (NP_005616).
Applications
Application Notes
WB: 1/500 - 1/2000; IHC-P: 1/150;
Target
Alternative Names
SDCBP; syndecan binding protein (syntenin); syntenin-1; SYCL; scaffold protein Pbp1; syndecan-binding protein 1; melanoma differentiation associated protein-9; melanoma differentiation-associated protein 9; pro-TGF-alpha cytoplasmic domain-interacting pro
Product Background
Antigen Description
Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.
Pathway
Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; IL-5 Signaling Pathway, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; Neurofascin interactions, organism-specific biosystem; Syndecan-1-mediated signaling events, organism-specific biosystem; Syndecan-2-mediated signaling events, organism-specific biosystem;
Citations
Publication ()
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COA
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