Anti-RSV Polyclonal antibody

It is controversial whether it is cost-beneficial for late preterm infants to receive respiratory syncytial virus prophylaxis. This study compares community and hospital health care resource utilization (HCRU) of late premature infants (33-36 weeks gestational age) with term infants (>36 weeks gestational age) hospitalized with bronchiolitis. This was a retrospective, population-based, observational study spanning a 9-year period (2004-2012). HCRU data were obtained from the Health Maintenance Organization "Clalit" and included duration of hospitalization, physician visits, laboratory tests, and treatments. Compared with term infants, late preterm infants had significantly longer duration of hospitalization and higher admission rates to pediatric intensive care unit. They also had higher rates of mean outpatients clinic visits, total outpatient clinic and specialist visits, blood chemistry, and virology testing. HCRU of term infants with bronchiolitis was also substantial, indicating that they also can greatly benefit from respiratory syncytial virus prophylaxis. These findings can guide stakeholders in decisions concerning the prevention of bronchiolitis and will be useful in performing further cost-benefit analysis.

Bacterial cellulose has unique structural, functional, physical and chemical properties. The mass production of bacterial cellulose for industrial application has recently become more popular and attractive. The aim of this study was to develop an efficient scale-up process of bacterial cellulose production. Bacterial cellulose productivity of a new isolate Acetobacter pasteurianus RSV-4 (MTCC 25117) was investigated in whey medium without addition of any additives. Produced bacterial cellulose was characterized for its structure, purity, thermostability and strength by Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, thermogravimetric analysis and Differential scanning calorimetry. beta-galactosidase (1.5 IU/ml) was used to split whey lactose into its corresponding monomers glucose and galactose. Glucose was specifically consumed by Acetobacter pasteurianus for the production of BC. The highest concentration of 5.6 g cellulose/L of whey was obtained at 30 degrees C after 8 days of bacterial growth. Process was optimized for the production of bacterial cellulose on 120 L of whey medium under static conditions. Whey, a waste byproduct of milk processing industry was used in the process and therefore the developed process might be economical.