Magic™ Anti-PAK2 polyclonal antibody (DPAB-DC1488)

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Bovine, Dog, Human, Mouse, Rat
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding T402 of rat Pak2.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1:1000; The optimal working dilution should be determined by the end user.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PAK2; p21 protein (Cdc42/Rac)-activated kinase 2; gamma-PAK; serine/threonine-protein kinase PAK 2; PAK-2; p21-activated kinase 2
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of Rac; Apoptosis; Axon guidance; CD28 co-stimulation

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Ding, JB; Knaus, UG; et al. The renaturable 69- and 63-kDa protein kinases that undergo rapid activation in chemoattractant-stimulated guinea pig neutrophils are p21-activated kinases. JOURNAL OF BIOLOGICAL CHEMISTRY 271:24869-24873(1996).
Sakurada, K; Kato, H; et al. Synapsin I is phosphorylated at Ser(603) by p21-activated kinases (PAKs) in vitro and in PC12 cells stimulated with bradykinin. JOURNAL OF BIOLOGICAL CHEMISTRY 277:45473-45479(2002).

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