Anti-PAK2 Polyclonal Antibody (CABT-L2226) Knockout Validated

Rabbit Anti-Human PAK2 (Glu177~Ala419) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Mouse
Immunogen
Recombinant fragment corresponding to human PAK2 (Glu177~Ala419)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.2-2 ug/ml; 1:250-2500
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type Jurkat cell lysate. Lane 2: PAK2 knockout Jurkat cell lysate. Predicted MW: 58kd, Observed MW: 58kd
Western Blot. Sample. Human Jurkat cell lysate.
Western Blot. Sample. Human Serum;
Western Blot. Sample. Mouse Spleen lysate.

Target


Alternative Names
PAK65; PAKgamma; p58; S6/H4 Kinase; Serine/threonine-protein kinase PAK 2
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of Rac; Adaptive Immune System; Apoptosis; Apoptotic execution phase; Axon guidance; C-MYC pathway; CD28 co-stimulation; CD28 dependent Vav1 pathway;

Citations


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References


Li, G; Hundemer, M; et al. Identification and characterization of HLA-class-I-restricted T-cell epitopes in the putative tumor-associated antigens P21-activated serin kinase 2 (PAK2) and cyclin-dependent kinase inhibitor 1A (CDKN1A). ANNALS OF HEMATOLOGY 85:583-590(2006).
Kissil, JL; Johnson, KC; et al. Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization. JOURNAL OF BIOLOGICAL CHEMISTRY 277:10394-10399(2002).

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