Anti-NO-L-Cysteine polyclonal antibody

Understanding cellular metabolism holds immense potential for developing new drugs that regulate metabolic pathways. Two gas signal molecules, SO2 and H2S, are the main metabolites from cysteine (Cys) via oxidation and desulfurization pathways, respectively. However, a few fluorescent probes for real-time monitor of the metabolic pathways of cysteine have been reported. To understand metabolic alterations of cysteine, we have rationally designed and prepared a dual-signal fluorescent probe HN, which could differentiate SO2 and H2S through two different fluorescence channels simultaneously, along with similar reaction kinetics and both "off-on" fluorescence responses. Probe HN exhibits the potential to monitor the metabolism pathways of cysteine, and the distinguishment of cancer cells from normal cells could be realized. This methodology will promote further understanding of the physiological and pathological roles of cysteine. (C) 2020 Elsevier B.V. All rights reserved.

Constructing a highly efficient, stable and cost-effective heterojunction nanostructure catalyst for the solar-tofuel conversion is critical but challenging. Herein, I reported the synthesis of c-cysteine (L-Cys) capped Ni2-xCoxP (0 <= x <= 2)/CdS heterostructures that enable efficient spatial charge separation and transfer for solar hydrogen generation. A unique covalent bond formed via L-Cys between NiCoP and CdS that produces vast number of heterojunctions and abundant catalytic active sites for H-2 production. FTIR and XPS results indicate that L-Cys capped NiCoP was tightly deposited on the surface of CdS through a covalent bond between thiol and Cd. The 40 wt% L-Cys capped NiCoP/CdS is found to have the best photocatalytic performance and led to excellent stability for 192 h. As a result, the L-Cys capped NiCoP/CdS composite exhibited a H-2 evolution rate of 218 mmol g(-1) h(-1) and achieved a very high apparent quantum yield of 76.3% at 420 nm.