Specifications
Antibody Isotype
IgG2a, κ
Immunogen
Endothelial cells isolated from BALB/c mouse mesenteric and peripheral lymph nodes.
Applications
Application Notes
IHC-Fr: 1 μg/ml.
Target
Alternative Names
MADCAM1; mucosal vascular addressin cell adhesion molecule 1; mucosal addressin cell adhesion molecule 1; Addressin mucosal; hMAdCAM 1; hMAdCAM-1; MACAM1; MADCA_HUMAN; MAdCAM-1; Madcam1; Mucosal addressin cell adhesion molecule 1; Mucosal vascular address
Product Background
Antigen Description
S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Pathway
Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Integrin cell surface interactions, organism-specific biosystem; Intestinal immune network for IgA production, organism-specific biosystem; Intestinal immune network for IgA production,
Citations
Publication ()
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COA
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