Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an immunoglobulin (Ig) cell adhesion molecule. MAdCAM-1 is involved in lymphocyte homing to mucosal sites and is expressed on high endothelial venules (HEV) of both mesenteric lymph nodes and Peyers patches. It has also been found on sinus-lining cells of the spleen.
Pathway
Adaptive Immune System; Cell adhesion molecules (CAMs); Extracellular matrix organization; Immune System; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Integrin cell surface interactions; Intestinal immune network for IgA produ
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