Specifications
Immunogen
CHO transfected cells expressing the B6 allele of NKG2A.
Applications
Application Notes
Flow Cyt: Neat - 1/5
General Notes
Clone 30e6 recognizes the mouse NKG2A, NKG2C and NKG2E antigen on a subset of NK and NK-T cells in most mouse strains (e.g. AKR/J, BALB/c, C3H/He,C57BL/6, CBA/J, DBA/1, FVB/N, 129/Sv, NOD, SWR, and most DBA/2 substrains, but not DBA/2J).
The recommended dilution of the antibody for staining is 1:10. Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
Target
Alternative Names
Klrc1; killer cell lectin-like receptor subfamily C, member 1; NKG2A; NKG2B; CD159a; NKG2-A/NKG2-B type II integral membrane protein; Cluster of Differentiation 159a
Product Background
Antigen Description
In mice, NKG2 subunits associate with CD94 to form heterodimers at the surface of natural killer (NK) cells.The CD94/NKG2 heterodimer is the receptor for a non-classical MHC class I ligand, which is Qa-1 in the mouse.
Pathway
ECM-receptor interaction; Focal adhesion; Integrin-mediated cell adhesion; Phagosome; Regulation of actin cytoskeleton
Citations
Publication ()
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COA
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